Our Familial Cancer Research Centre combines clinical and laboratory-based research to:
- Identify new hereditary cancer predisposition genes
- Improve the identification of people with hereditary cancer syndromes
- Develop new strategies for cancer risk management and personalising cancer treatments
- Investigate the wider psychosocial impact of these syndromes on the wellbeing of individuals and their families through the work of the Psychosocial Cancer Genetics Research Group
- The Familial Cancer Research Centre is leading on several research projects that include:
- Investigating the role those common genetic variations (of the type we all have) play in inherited breast and ovarian cancer risk
- Building a partnership between Australian Familial Cancer Centres (FCCs) to transform their clinical practice into a research resource
- Studying prostate cancer screening in men with inherited BRCA and mismatch repair (MMR) gene mutations
Familial Cancer Research Centre research focus
Our research focus includes:
- Identifying people with hereditary cancer syndromes and stratifying their individual cancer risk.
- Developing, implementing, and validating new strategies of cancer risk assessment and management, including genetic counselling models and preventative medicines.
- Identifying and validating new cancer risk predisposition genes through laboratory research.
Research programs and projects
- Recruiting
- PRiMo Trial
- ViP: Variants in Practice
Ongoing
- Annual review program for gene carriers
- IMPACT: Targeted prostate cancer screening
- Hereditary contribution to ovarian cancer
- ICCon (Inherited Cancer Connect Partnership) database
- ICCon: The Inherited Cancer Connect partnership
- eviQ Audit: Survey and audit of Familial Cancer Clinics
- Psychosocial Cancer Genetics Research
Location
Familial Cancer Centre
Level 1, Peter MacCallum Cancer Centre
305 Grattan Street
Melbourne VIC 3000
Contact
Familial Cancer Centre
- Phone: (03) 8559 5322
- Fax: (03) 8559 5329
- Email: [email protected]
Further information
The Familial Cancer Research Centre collaborates with and contributes to several large collaborative studies including:
- The Australian Ovarian Cancer Study (AOCS): Defining the hereditary contribution to ovarian cancer: The role of mismatched repair genes
- Mammographic Screening: Improving population based mammographic screening
- Ovarian Cancer Program: Improving outcomes for women with Ovarian Cancer
- Lifepool - The NBCF (National Breast Cancer Foundation) BreastScreen Cohort Demonstration Project: Integration of Breastscreen with an epidemiological, molecular, and translational research program
- BRCAX – WES: Identification of novel breast and ovarian cancer susceptibility genes
- kConFab: The Kathleen Cuningham foundation consortium for research into familial breast cancer