Cancer surgery and anaesthetic clinical trials - Peter MacCallum Cancer Centre

If you would like to be considered for a clinical trial you will require a referral from your current treating team. Visit the Joining a Clinical Trial page for referral information.

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Open and Recruiting Clinical Trials

ROCKet

A clinical trial to test if Ketamine administration during and after surgery will reduce the risk of patients developing long term pain after surgery

Trial ID

ACTRN12617001619336

Cancer Type

Not specific

Status

Open and recruiting

Phase

3 / 4

Brief summary

The aim of this study is to see if giving the drug Ketamine during surgery and for up to three days after reduces development of chronic post-surgical pain in patients having breast, chest or abdominal surgery. Participants are randomly assigned to receive either the drug ketamine or placebo (normal saline) during and after surgery. All participants:

Complete questionnaires prior to surgery and before discharge from hospital
Answer follow up questions over the phone three months and one year following surgery
Have information accessed regarding visits to their GP and any pain medication scripts needed postoperatively (if consenting)

Who can participate

Adult patients who:

Are having breast, chest or abdominal surgery
Require a hospital stay of at least one night following surgery
Do not have a history of stroke, epilepsy or complex regional pain syndrome

For full inclusion / exclusion criteria refer to the Australian Cancer Clinical Trial Registry.

If you don’t find what you are looking for or would like a center closer to home that may also provide similar clinical trials, refer to the Victorian Cancer Trials Link or Australian Clinical Trials Registry.