Phase IV RCT study to assess the safety and efficacy of methoxyflurane (Penthrox™) for the treatment of incident pain in patients undergoing a bone marrow biopsy procedure

Methoxyflurane is a fluorinated ethyl methyl ether analgesic anaesthetic agent which has been administered via a hand held device, in prehospital ambulance transfers for patients in pain for many years.

This placebo-controlled study aimed to assess analgesic efficacy in patients undergoing bone marrow biopsy and to assess the safety of use in this population.

SPONSOR

Medical Developments International

Funding

Medical Developments International

Principal Investigator/s

A/Prof Odette Spruyt

Palliative care consultant

Contact

A/Prof Odette Spruyt

Principal Investigator

Email: [email protected]

Publications & presentations

Spruyt, O, Westerman, D., Milner, A., Wein, S. A randomized, double-blind, single centre, placebo-controlled study to assess the safety and efficacy of Methoxyflurane for bone marrow-associated procedural pain. BMJ Supportive & Palliative Care 2013; 00:1-7.

Spruyt O, Westerman D, Lipshut S. Wein S. A randomised, double-blind, single centre, placebo-controlled phase IV study to assess the safety and efficacy of methoxyflurane (Penthrox™). EAPC 7th World Research Congress Trondheim, Norway