Professor Alicia Oshlack has been at the forefront of bioinformatics research for more than 15 years. She is the Head of the Computational Biology Program and group leader at the Peter MacCallum Cancer Centre. She is best known for her large body of work on transcriptional analysis and medical genomics. In addition, Oshlack is internationally recognised for her development of bioinformatics methods for a range of applications including single cell RNA-seq, methylation and genomic analysis. Oshlack is involved in many cutting edge collaborative projects utilising high throughput sequencing to investigate disease and development. She has published more than 100 papers and has developed more than a dozen software packages. Oshlack has been recognised by several awards including the Australian Academy of Science, Gani Medal for Human Genetics (2011) and the Georgina Sweet Award for Women in Quantitative Biomedical research (2016) and was recently elected as a member of the Australian Academy of Health and Medical Science.