The Hogan lab investigates the lymphatic vasculature and the blood brain barrier, which play important roles in metastasis.
Ben Hogan completed his PhD in developmental biology at the Ludwig Institute for Cancer Research in 2005. Following a year as a Cancer Council Victoria Fellow, he moved to the Hubrecht Institute for Stem Cell and Developmental Biology (Netherlands) to study the vasculature. This work was supported by an EMBO fellowship and an NHMRC CJ Martin Fellowship. During this time, he uncovered the role of Ccbe1 in lymphangiogenesis and was part of a team that characterised CCBE1 mutations in generalized lymphoedema in humans. This work was awarded the Postdoctoral Investigators Award from the NARF of the NHMRC in 2009.
Ben founded his own research team at the Institute for Molecular Bioscience, University of Queensland in 2010. Work from his group has since led to discovery of a number of genes essential for angiogenesis and lymphangiogenesis, characterization of molecular mechanisms controlling the CCBE1/VEGFC/VEGFR3 signalling axis and description of new cellular processes involved in vessel formation in live tissues. During his time in QLD, he was supported by an ARC Future Fellowship, an NHMRC/Heart Foundation Career Development Fellowship and received the Emerging Leader Award of the ANZSCDB (2016).
His group relocated to the Petermac and the University of Melbourne in 2019. Professor Hogan is an NHMRC Senior Research Fellow and his work is currently funded by grants from the NHMRC, ARC and Bright Focus Foundation (USA).