Dr Lachlan McDowell is a Consultant Radiation Oncologist at the Peter MacCallum Cancer Centre specialising in the treatment of head and neck cancers. He graduated from the University of Queensland in 2008, and received his Fellowship in Radiation Oncology from the Royal Australian and New Zealand College of Radiologists in 2015. During 2015, he undertook a clinical and research fellowship in head and neck radiation oncology and adult radiation therapy late effects at the Princess Margaret Hospital, Toronto, Canada. He joined the Peter Mac radiation oncology unit in December 2016.
Dr McDowell’s main research interests include clinical outcomes and health related quality of life in head and neck cancers. He is currently enrolled in a Doctor of Philosophy at the University of Melbourne focussed on gaining a better understanding of the long-term quality of life and unmet needs of survivors with human papillomavirus-associated (HPV) oropharyngeal cancer. He is also a supervisor and investigator of a number of local cohort and clinical studies.
Dr McDowell is an active member of the Trans-Tasman Radiation Oncology Group (TROG) Head and Neck and Skin Cancer working party, and is the radiation oncology primary investigator for two clinical trials being developed through TROG. He is also a member of the scientific committee of the Australian and New Zealand Head and Neck Cancer Society. He also has memberships with the American Society for Radiation Oncology (ASTRO) and the European Society for Therapeutic Radiation Oncology (ESTRO). He has previously been involved in the development of national treatment guidelines for head and neck cancer as a member of the EVIQ reference committee.
Dr McDowell has published in internationally recognized oncology journals including Cancer, International Journal of Radiation Oncology Biology Physics. Radiotherapy and Oncology, Oral Oncology, Head & Neck and the Journal Of Medical Imaging and Radiation Oncology. He is also regularly peer reviews for a number of international oncology journals.
Dr McDowell was also the recipient of the 2018 award for excellence in teaching in the Victorian and Tasmanian radiation oncology training network. He has previously received honourable mentions in 2016 and 2017.
Textbook of Uncommon Cancers. 5th Edition. Wiley-Blackwell, 2017. Chapter 8: Nasopharyngeal Carcinoma in the Non-endemic populations. Lachlan McDowell, Annette Lim, June Corry.
The Use of Antibiotics: A Clinical Review of Antibacterial, Antifungal and Antiviral Drugs. Holder Arnold - Health Sciences, 2010. Chapter: ‘Ceftriaxone’. Lachlan McDowell, Baek-Nam Kim, David Patterson
McDowell L, Corry J. Comment on "Ipsilateral neck radiotherapy in N2b well-lateralized tonsil cancer-Approach with caution". Head Neck. 2019 Jun 28. doi: 10.1002/hed.25855. [Epub ahead of print] PubMed PMID: 31250944.
McDowell L, Corry J. Radiation therapy quality assurance in head and neck radiotherapy - Moving forward. Oral Oncol. 2019 Jan;88:180-185.. Epub 2018 Dec 10. PubMed PMID: 30616792.
McDowell LJ, Corry J. A Call to Arms: Radiation Therapy Quality Assurance in the Next Generation of Clinical Trials. Int J Radiat Oncol Biol Phys. 2018 Dec 1;102(5):1590-1591. doi: 10.1016/j.ijrobp.2018.07.2001. Epub 2018 Jul 29. PubMed PMID: 30063942.
McDowell LJ, Young RJ, Johnston ML, Tan TJ, Kleid S, Liu CS, Bressel M, Estall V, Rischin D, Solomon B, Corry J. p16-positive lymph node metastases from cutaneous head and neck squamous cell carcinoma: No association with high-risk human papillomavirus or prognosis and implications for the workup of the unknown primary. Cancer. 2016 Apr 15;122(8):1201-8. doi: 10.1002/cncr.29901. Epub 2016 Feb 16. PubMed PMID: 26881928.
McDowell LJ, Huang SH, Xu W, Che J, Wong RKS, Brierley J, Kim J, Cummings B, Waldron J, Bayley A, Hansen A, Witterick I, Ringash J. Effect of Intensity Modulated Radiation Therapy With Concurrent Chemotherapy on Survival for Patients With Cervical Esophageal Carcinoma. Int J Radiat Oncol Biol Phys. 2017 May 1;98(1):186-195. doi: 10.1016/j.ijrobp.2017.01.003. Epub 2017 Jan 9. PubMed PMID: 28258892.
McDowell LJ, Rock K, Xu W, Chan B, Waldron J, Lu L, Ezzat S, Pothier D, Bernstein LJ, So N, Huang SH, Giuliani M, Hope A, O'Sullivan B, Bratman SV, Cho J, Kim J, Jang R, Bayley A, Ringash J. Long-Term Late Toxicity, Quality of Life, and Emotional Distress in Patients With Nasopharyngeal Carcinoma Treated With Intensity Modulated Radiation Therapy. Int J Radiat Oncol Biol Phys. 2018 Oct 1;102(2):340-352. doi: 10.1016/j.ijrobp.2018.05.060. Epub 2018 Jun 4. PubMed PMID: 30191868.
McDowell LJ, Ringash J, Xu W, Chan B, Lu L, Waldron J, Rock K, So N, Huang SH, Giuliani M, Hope A, O'Sullivan B, Bratman SV, Cho J, Kim J, Jang R, Bayley A, Bernstein LJ. A cross sectional study in cognitive and neurobehavioral impairment in long-term nasopharyngeal cancer survivors treated with intensity-modulated radiotherapy. Radiother Oncol. 2019 Feb;131:179-185. doi:10.1016/j.radonc.2018.09.012. Epub 2018 Sep 29. PubMed PMID: 30279047.
McDowell LJ, Tan TJ, Bressel M, Estall V, Kleid S, Corry J, Johnston ML. Outcomes of cutaneous squamous cell carcinoma of the head and neck with parotid metastases. J Med Imaging Radiat Oncol. 2016 Oct;60(5):668-676. doi: 10.1111/1754-9485.12484. Epub 2016 Jun 21. PubMed PMID: 27324298.
McDowell LJ, Jacobson MC, Levin W. High-dose intravenous steroid regimen for radiation-induced hypoglossal nerve palsy. Head Neck. 2017 Feb;39(2):E23-E28. doi: 10.1002/hed.24600. Epub 2016 Oct 5. PubMed PMID: 27704653.
Hirshoren N, Ruskin O, McDowell LJ, Magarey M, Kleid S, Dixon BJ. Management of Parotid Metastatic Cutaneous Squamous Cell Carcinoma: Regional Recurrence Rates and Survival. Otolaryngol Head Neck Surg. 2018 Aug;159(2):293-299. doi: 10.1177/0194599818764348. Epub 2018 Mar 13. PubMed PMID: 29533706.
Bucknell NW, Dixon BJ, Hoffman MS, McDowell LJ. Importance of timing in staging head and neck cancer: cervical adenopathy post-tonsillectomy mimicking malignancy. ANZ J Surg. 2018 Apr 25. doi: 10.1111/ans.14509. [Epub ahead of print] PubMed PMID: 29695024.
Ong WL, Bailey E, McCormack C, Weston L, Morgan V, McDowell L. Definitive radiotherapy for Merkel cell carcinoma in the setting of epidermolysis bullosa simplex. Australas J Dermatol. 2019 May;60(2):153-154. doi: 10.1111/ajd.12960. Epub 2018 Nov 18. PubMed PMID: 30450568.
McDowell L, Collins M, Kleid S, Rischin D, Corry J. T4 squamous cell carcinoma of the oral tongue without mandibular involvement: surgery or chemoradiotherapy? Oral Surg Oral Med Oral Pathol Oral Radiol. 2014 Feb;117(2):163-9. doi: 10.1016/j.oooo.2013.09.005. Epub 2013 Nov 23. PubMed PMID: 24275355.