Chemotherapy drugs and safety

Safety and chemotherapy

The types of drugs used for chemotherapy are strong. They can remain in the body for up to a week after treatment and can be passed through bodily fluids. Friends and family, including children and pregnant women, can visit while you are having chemotherapy as long as you follow safety precautions:

  • Put down the lid of the toilet seat when flushing to avoid splashing.
  • Wash any clothing or bedding soiled with body fluids thoroughly and in a separate load. Wear rubber gloves when handling soiled clothes or linen.
  • If body fluids or chemotherapy medications spill wear rubber gloves, soak up with paper towel, wipe with soapy water and a disposable cloth and rinse well with water.
  • Seal used gloves and cleaning cloths in a bag before throwing them away.
  • If chemotherapy drugs come into contact with skin, rinse well with soap and running water and contact the hospital if irritation occurs and does not resolve itself within an hour.
  • Use protection for any sexual intercourse and avoid pregnancy.
  • Do not breast feed.
  • Don't crush or break chemotherapy tablets.
  • Store chemotherapy medications as directed by your treating team. Do not store them directly with other medications.
  • Seal empty medication containers in a plastic bag and return them to your hospital or pharmacy for disposal.

For more information about safety during chemotherapy, speak to your treating team.

Types of chemotherapy drugs

There are many different types of chemotherapy drugs that are used to treat many different types of cancer. Some of the chemotherapy drugs used at Peter Mac are listed below. For more information regarding the chemotherapy or other treatments you or your loved one is receiving please speak to your doctor, nurses or pharmacist.

ChemotherapyDescription
5FU Folinic Acid (Roswell park) and 5FU Folinica Acid (weekly)Chemotherpy drug 5 Fluorouracil and folinic acid (used to increase activity of 5FU) used in the treatment of colorectal cancer
ABVD - Adriamycin - Bloemycin, Vinblastine and DacarbazineA combination of Doxorubicin (also called Adriamycin) used in the treatment of Hodgkin's lymphoma
AC-PCombination of Doxorubicin and Cyclophophamide, followed by Paclitaxel used in the treatment of breast cancer
ACCombination of Doxorubicin (also called Adriamycin) and Clyclophosphamine used in the treatment of breast cancer
ADCombination of Doxorubicin (Adriamycin) and dexamethasone used in the treatment of multiple myeloma
BEACOPPCombination of Bleomycin, Etoposide, Doxorubicin (Adriamycin) Cyclophophamide, Vincristine (Oncovin), Prendnisolone and Procarbazine used in the treatment of Hodgkin's lymphoma
BEPCombination of Bleomycin, Etoposide and Cisplatin (Platinum) used in the treatment of testicular cancer
Carboplatin / 5-FlurouracilCombination of chemotherapy used in the treatment of various cancers
Carboplatin / EtopsodieCombination of chemotherapy used in the treatment of various cancers
Carboplatin / Paclitaxel (also known as Taxol ® ) - 3 weekly gynecologicalCombination of chemotherapy used in the treatment of gynecological cancers
Carboplatin / Paclitaxel (also known as Taxol ® ) - 3 weeklyCombination of chemotherapy used in the treatment of various cancers
Carboplatin / Paclitaxel (also known as Taxol ® ) - Weekly combined RT lung regimeCombination of chemotherapy used in the treatment of lung cancer in combination with radiotherapy treatment
Carboplatin / Pemetrexed (Alimta®)Combination of chemotherapy used in the treatment of mesothelioma
CarboplatinUsed to treat people with various types of cancers
CEF (oral)Combination of Cyclophosphamide, Epiribucin and 5-Fluorouracil
(5-FU) used in the treatment of breast cancer
CFCombination of Cisplatin and 5Fluorouracil
(5FU) and is used in the treatment of cancer of the oesophagus and some other types of cancer
CHOPCombination of Cyclophosphamide, Doxorubicin , Vincristine (also called Oncovin) and Prednisolone used in the treatment of some types of non-Hodgkin’s lymphoma
Cisplatin / Etoposide NSCLCCombination of chemotherapy used in the treatment of some non-small cell lung cancer. It is given in combination with radiotherapy treatment.
Cisplatin / Etoposide SCLCCombination of chemotherapy used in the treatment of some small cell lung cancer. It may be given in combination with radiotherapy treatment
Cisplatin and Pemetrexed (also known as Alimta®)Combination of chemotherapy used as a treatment for people with mesothelioma
Cisplatin / VinorelbineCombination of chemotherapy used as a treatment for people with lung cancer
CisplatinUsed in the treatment of various types of cancer
CMF (oral)Combination of Cyclophosphamide, Methotrexate and 5 Fluorouracil (5FU). Used in the treatment of breast cancer
CVPCombination of Cyclophosphamide, Vincristine and
Prednisolone used in the treatment of non-Hodgkin’s lymphoma
DacarbazineUsed in the treatment of melanoma and some other cancers. It is sometimes called DTIC
Docetaxel (also known as Taxotere®)Used in the treatment of various types of cancer and the treatment of some breast cancers
Doxorubicin (also known as Adriamycin)Used in the treatment of various types of cancer
E-CMFCombination of Epirubicin followed by Cyclophosphamide,
Methotrexate and 5-Fluorouracil (5-FU) and used in the treatment of breast cancer
ECFcombination of Epirubicin, Cisplatin and 5Fluorouracil
(5FU) used in the treatment of stomach and oesophageal cancers
FCCombination of Fludarabine and Cyclophosphamide used in the treatments of some types of leukaemia
FECCombination of 5-Fluorouracil (also known as 5FU), Epirubicin
and Cyclophosphamide and is used in the treatment of breast cancer
FOLFIRICombination of 5Fluorouracil (5FU), Folinic Acid (leucovorin) and Irinotecan used in the treatment of colorectal cancer
Modified FOLFOXCombination of Folinic acid (also called leucovorin), 5Fluorouracil
(5FU), and Oxaliplatin used in the treatment of colorectal cancer. It is called modified FOLFOX as the chemotherapy drugs are given in a slightly different (simplified) way to other FOLFOX regimes
FOLFOX4 and FOLFOX6Combination of Folinic acid (also called Leucovorin), 5Fluorouracil
(5FU), and Oxaliplatin used in the treatment of colorectal cancer
FotemustineUsed in the treatment of melanoma
Gemcitabine and CarboplatinCombination of chemotherapy used in the treatment of various types of cancer
GemcitabineUsed in the treatment of many different types of cancer
Infusional 5FU (concurrent RT)5Fluorouracil (5FU) in combination with radiotherapy is used in the treatment of many different types of cancer
IrinotecanUsed in the treatment of colorectal cancer
Liposomal Doxorubicin (also known as Caelyx®)Used in the treatment of some type of cancers
Mitomycin C and 5Flurouracil
(5FU)
Combination of chemotherapy drugs used with radiotherapy used in the treatment of anal cancer
Paclitaxel (also known as Taxol®)Used as a treatment for various types of cancer
Pemetrexed (also known as Alimta®)Used in the treatment of non-small cell lung cancer and mesothelioma
TCCombination of Docetaxel (also known as Taxotere®) and
Cyclophosphamide used in the treatment of breast cancer
TCHCombination of the chemotherapy drugs Docetaxel (also known as Taxotere®) and Carboplatin
and the monoclonal antibody Trastuzumab (also known as Herception®) which uses the natural immune system to kill tumour cells. It is used in the treatment of breast cancer
TopotecanUsed in the treatment of various types of cancer
XeloxCombination of oxaliplatin and capecitabine (Xeloda ® ) used in the treatment of colorectal cancer

At Peter Mac we also use some therapies that may be used in conjunction with your chemotherapy or alone to treat disease. These are not chemotherapy drugs, however are usually delivered in the same ways, most commonly in the Day treatment Unit. These include:

TreatmentDescription
Monoclonal AntibodiesMolecules that mimic the natural antibodies that act as part of your bodies immune system to fight infection, germs and foreign invaders. They target cancer cells in different ways to chemotherapy.
BevacizumabUsed in the treatment of several cancers, including colorectal and breast cancer. It is usually used in combination with chemotherapy
Cetuximab (Erbitux ® )Used in the treatment of several cancers, including colorectal and cancers of the head and neck. May be given in combination with chemotherapy, or alone.
Rituximab (Mabthera®)Used in the treatment of some types of non-Hodgkin's lymphoma and leukemia.
Trastuzumab (Herceptin®)Used in the treatment of breast cancer. Herceptin attaches itself to the HER2 protien which is found in high amounts on the surface of SOME breast cancers.
Biological TherapiesThe use of a derivative of living organisms, the living organism themselves of a synthetic versions of these to treat cancers.
Bortezomib (Velcade®)A proteasome inhibitor used in the treatment of Multiple Myeloma
InterferonInterferons are naturally occurring proteins that help stimulate the body's immune system when a foreign substance is detected in the body (like an infection). They are used to stimulate the immune system and reduce the ability of cancer cells to protect themselves.

Who can I call for help?

In the case of a MEDICAL EMERGENCY CALL 000

You can speak to medical or nursing staff 24 hours a day, seven days a week at Peter Mac.

Monday to Friday, between 8 am and 6 pm, call: Day Therapy on (03) 8559 5330

Outside these hours (evenings, weekends and public holidays), call: (03) 8559 5000 and ask for the Patient Services Manager

Please have your hospital PUR number ready when you call the hospital.

Cancer Council’s 13 11 20 is open Monday to Friday, 9 am to 5 pm, and staffed by experienced cancer nurses who can support those affected by cancer, their carers and loved ones by providing emotional and practical support.

Location

Day Therapy

Level 3, Peter MacCallum Cancer Centre

305 Grattan Street

Melbourne 3000

Contact

Day Therapy

Phone: 03 8559 5330